Upcoming Webinars Archived Webinars Training Vitals Host A Webinar About Get Updates Contact

Small Study Of Novartis Asthma Drug Shows Promising Results

XTALKS VITALS NEWS

Asthma

The oral drug is a departure from traditional asthma inhalers, in which the medication is delivered directly into the lungs.

Tweetables from this article:

Tweet: #Asthma drug could lower inflammatory #biomarkers more effectively when compared to the placebo http://ctt.ec/c_o6b+Asthma drug could lower inflammatory biomarkers more effectively when compared to the placebo.

Tweet: By the year 2020, the US market for #asthma drugs is expected to reach $14 billion http://ctt.ec/P0dpl+By the year 2020, the US market for asthma drugs is expected to reach $14 billion.

Share this!

August 9, 2016 | by Sarah Massey, M.Sc.

An experimental asthma medication developed by Novartis has shown promising results in a recent small investigational study. The results – which were published in the journal, The Lancet Respiratory Medicine – suggest that the drug could lower inflammatory biomarkers more effectively when compared to the placebo.

The trial involved 61 patients who were randomly assigned to receive the experimental drug, called fevipiprant, or a placebo. The drug is a prostaglandin D2 receptor 2 antagonist, and was successful at significantly reducing the eosinophil count in those with moderate to severe asthma.

The oral drug is a departure from traditional asthma inhalers, in which the medication is delivered directly into the lungs. According to Reuters, the Swiss drugmaker hopes to file for regulatory approval in 2019.



To meet that goal, Novartis will need to conduct further studies involving more patients in order to prove the efficacy of fevipiprant. If approved, the drug could be the first new oral treatment for asthma since the 1950s.

By the year 2020, the US market for asthma drugs is expected to reach $14 billion, according to GBI Research. In 2013, the market was worth $11.7 billion.

While pharma giants GlaxoSmithKline, Merck and AstraZeneca are all major players in the asthma space, Novartis is hoping to gain market share with fevipiprant. As much of the R&D into new asthma therapies has focused on inhaled drugs, most of the top-selling medications for the respiratory condition utilize that form of drug delivery.

The current study was conducted at Glenfield Hospital in Leicester, UK. Fevipiprant was described as having a good safety profile, with no serious adverse events reported.


Keywords: Asthma, Biomarker, Drug Delivery


| NEXT ARTICLE | MORE NEWS | BLOGS | VIDEOS | POLLS & QUIZZES | WEBINARS |

Share this with your colleagues!

MORE NEWS
Researchers Identify Role of ApoE4 Gene as Possible Drug Target in Alzheimer’s Disease

September 21, 2017 - A team of neurology researchers at Washington University School of Medicine in St. Louis have found that in the presence of the ApoE4 protein, another protein known as tau forms tangles in the brain which contributes to neuronal damage characteristic of Alzheimer’s disease.

Featured In: Life Science News


New Guidelines Address CAR-T Immunotherapy Toxicities to Prevent Patient Deaths

September 20, 2017 - Clinicians at The University of Texas MD Anderson Cancer Center have published new guidelines in the journal, Nature Reviews Clinical Oncology, which could help in the management of these toxicities.

Featured In: Biotech News, Drug Safety News


Microneedle Skin Patch Could Treat Common Metabolic Disorders

September 19, 2017 - Researchers at Columbia University Medical Center (CUMC) and the University of North Carolina have developed a microneedle skin patch impregnated with a drug capable of converting white fat into calorie-burning brown fat.

Featured In: Medical Device News


LEAVE A COMMENT
 
  
THE XTALKS VITALS INDUSTRY BLOG

Five Reasons Why Toronto is Emerging as a Major Life Sciences Hub

REGISTER FOR THESE WEBINARS

Development and Manufacture of Highly Potent API Drug Products Throughout the Clinical Phases


Innovation through Integration – Providing Next Generation Biomedical Devices and Interconnects


Clinical Payments Case Studies: Improving Efficiency, Cash Management, and Compliance


Why Phase 3 Trials Fail: Oncology Case Studies and Lessons Learned


Copyright © 2016-2017 Honeycomb Worldwide Inc.