Upcoming Webinars Archived Webinars Training Vitals Host A Webinar About Get Updates Contact

Novartis’ Heart Drug Could Save 28,000 US Heart Failure Patients Each Year

XTALKS VITALS NEWS

Heart Failure

According to the researchers in the latest study, if all 2.2 million eligible patients were to use Entresto, the drug could delay or prevent 28,484 deaths, per year.

Share this!

Tweet: Novartis' Entresto could prevent 28,000 #heartfailure deaths in the US each year. http://ctt.ec/bfb8l+Novartis' Entresto could prevent 28,000 heart failure deaths in the US each year.

Tweet: Novartis' Entresto to be more cost-effective compared to the standard of care treatment. http://ctt.ec/sSbm0+Novartis' Entresto to be more cost-effective compared to the standard of care treatment.

June 28, 2016 | by Sarah Massey, M.Sc.

A new study published in the journal, JAMA Cardiology, suggests that Novartis’ Entresto could prevent 28,000 heart failure deaths in the US each year. It’s estimated that 2.7 million patients in the US are affected by a specific type of heart failure – known as heart failure and reduced ejection fraction – and approximately 84 percent of this patient population could be candidates for treatment with Entresto.

An additional study – also published in JAMA Cardiology – found treatment with Entresto to be more cost-effective compared to the standard of care treatment, the angiotensin-converting enzyme (ACE) inhibitor, enalapril. Despite launching the heart drug last year, Novartis has seen slow sales of Entresto. The company hopes that this latest data will help boost Entresto’s market presence.

According to the researchers in the latest study, if all 2.2 million eligible patients were to use Entresto, the drug could delay or prevent 28,484 deaths, per year. Based on the results, the researchers say that putting off treatment with the drug could have “substantial downsides.”



The number of eligible patients was estimated based on the drug’s label restrictions, however the study authors admit that the actual number of ineligible patients could be higher. This, along with the increased costs associated with widespread treatment with Entresto, could change the conclusions reached by the researchers.

An earlier clinical trial sponsored by Novartis, found that Entresto reduced the risk of heart failure-related hospitalizations and death by 20 percent, and lowered overall mortality by 16 percent. Despite initial costs, over a 30-year period, treatment with Entresto has been estimated to be more cost-effective than current treatments.

In an effort to collect further supporting data for the drug, Novartis has expanded their clinical trials of the drug. In the face of increasing generic competition, Novartis is hopeful that the heart drug will help boost revenue.


Keywords: Heart Failure, Heart Drug, Clinical Trial


| NEXT ARTICLE | MORE NEWS | BLOGS | VIDEOS | POLLS & QUIZZES | WEBINARS |

Share this with your colleagues!

MORE NEWS
Study Finds Hospital-Acquired Anemia Linked with Poorer Patient Outcomes

May 19, 2017 - New research conducted at UT Southwestern Medical Center has found that one in three patients admitted to hospital develop anemia as a result.

Featured In: Life Science News


Scott Gottlieb Takes the Helm of the FDA

May 18, 2017 - One of the first things on his regulatory agenda is to address drug pricing – a hot topic in the US pharmaceutical industry today.

Featured In: Pharmaceutical News


Opioid Prescriptions for Minor Injuries Contribute to Growing Epidemic

May 18, 2017 - While many assume that patients prescribed large quantities of opioid drugs – such as oxycodone – for chronic pain are at the highest risk of abuse and dependence, new research suggests that small prescriptions for these narcotic painkillers could be just as dangerous.

Featured In: Drug Safety News


LEAVE A COMMENT
 
  
THE XTALKS VITALS LIFE SCIENCE BLOG

Top 5 Most Impactful Tweets in Life Sciences During the Last Week

REGISTER FOR THESE WEBINARS

The ABCs of Assessing Cognition in Oncology Clinical Trials: Applications, Benefits, and Considerations


Respiratory Endpoints, Scientific Leadership and the Asia-Pacific Region


Imaging Diagnostics and Theranostics: Meeting Clinical Development Challenges


Enabling Patient-Centric Digital Transformation in Pharma and Biotech


Copyright © 2016-2017 Honeycomb Worldwide Inc.