Upcoming Webinars Archived Webinars Training Vitals Host A Webinar About Get Updates Contact

New Drug Manufacturing Technology Could Improve Personalized Medicine

XTALKS VITALS NEWS

3-D Printing

According to the researchers, this new tablet fabrication method will allow drugmakers to combine multiple different pharmaceuticals – with different rates if release – into a single pill.

Share this!

May 27, 2016 | by Sarah Massey, M.Sc.

Engineers from the National University of Singapore (NUS), have developed a new way to manufacture personalized medicine that is less expensive and more convenient than currently-available methods. According to the researchers, this new tablet fabrication method will allow drugmakers to combine multiple different pharmaceuticals – with different rates if release – into a single pill Tweet: Combine multiple different pharmaceuticals – with different rates if release – into a single pill. http://ctt.ec/68NbM+.

In order to get the optimal therapeutic effect from a given medication, the drugs must be released at a set rate to be absorbed by the body. This means that patients taking multiple medications must take them on a complicated schedule, making sure to take some drugs together and avoid combining others.

Current tablet manufacturing methods – including 3-D printing – do provide some level of design flexibility, however these methods have many limitations. Most existing drug production methods can only produce low-dose pills that are released following a non-continuous profile. Assistant Professor Soh Siowling and PhD student Ms. Sun Yajuan from the Department of Chemical and Biomolecular Engineering at the NUS Faculty of Engineering, say their system will solve many of these problems.

“For a long time, personalized tablet has been a mere concept as it was far too complex or expensive to be realized,” said Siowling. “This new tablet fabrication method is a game changer – it is technically simple, relatively inexpensive and versatile. It can be applied at individualized settings where physicians could produce customized pills on the spot for patients, or in mass production settings by pharmaceutical companies.”



In contrast to other 3-D printing methods which build the tablet one layer at a time, the tableting process designed by Siowling and his colleagues is composed of three different components. One of these components – a specialized polymer – contains the drug, which can be manufactured in a specific shape to ensure optimal release of the payload.

According to the researchers, physicians may be able to use this method to print personalized treatments for patients at the point-of-care. The system would only require the doctor to input the drugs’ desired release profile into a computer software program, and use a standard 3-D printer to fabricate the tablets.

As it’s often necessary for patients to take multiple drugs at once, the researchers say this method could be used to manufacture pills containing multiple active pharmaceutical ingredients. By adjusting the shape of each polymer-associated drug, a single pill with multiple drug release profiles can be made.


Keywords: Personalized Medicine, Drug Manufacturing, 3-D Printing


| NEXT ARTICLE | MORE NEWS | BLOGS | VIDEOS | POLLS & QUIZZES | WEBINARS |

Share this with your colleagues!

MORE NEWS
Kite Pharma Secures FDA Approval for CAR-T Immunotherapy

October 20, 2017 - Kite Pharma’s Yescarta (axicabtagene ciloleucel) has become the second CAR-T immunotherapy to be approved in the US, with an indication in treating adult patients with relapsed or refractory large B-cell lymphoma.

Featured In: Biotech News


Fallopian Tubes Found to be Site of Origin for Most Ovarian Cancers

October 20, 2017 - This year, over 22,000 women will be diagnosed with ovarian cancer but a new study conducted by researchers at Perlmutter Cancer Center at NYU Langone Health suggests that most of these malignancies begin in another part of the reproductive system: the fallopian tubes.

Featured In: Life Science News


Food Companies are Looking for the Next Sriracha

October 19, 2017 - The Sriracha trend might be coming to an end and companies are looking for the next big hot sauce star to feature in their line-up.

Featured In: Food News


LEAVE A COMMENT
 
  
THE XTALKS VITALS INDUSTRY BLOG

Five Reasons Why Toronto is Emerging as a Major Life Sciences Hub

REGISTER FOR THESE WEBINARS

Brexit – Separating Fact from Fiction


Evolving Best Practices for Working with Authors of Scientific Publications – Authorship and Beyond


Human Whole-Genome Sequencing in a New Era Defined by the Illumina® HiSeq X® and NovaSeq™ Platforms


Clinical Event Adjudication: Comprehensive and Efficient Dossier Review Using a Global On-Line Solution


Copyright © 2016-2017 Honeycomb Worldwide Inc.