Upcoming Webinars Archived Webinars Training Vitals Host A Webinar About Get Updates Contact

Takeda Begins Phase IIb Clinical Trial Of Norovirus Vaccine

XTALKS VITALS NEWS

Vaccine

According to Takeda, an earlier clinical trial of the norovirus vaccine found that the drug was well tolerated among the 98 trial participants, but did not significantly reduce diarrhea or vomiting symptoms.

Share this!

June 22, 2016 | by Sarah Massey, M.Sc.

The only vaccine currently in development to prevent norovirus infection has just entered a Phase IIb clinical trial. The developer of the vaccine – Takeda Pharmaceuticals – has started dosing patients to assess the efficacy of the norovirus vaccine candidate.

Tweet: Takeda Pharmaceuticals is dosing patients with #norovirus vaccine candidate http://ctt.ec/GIkYD+

Norovirus is a highly-infectious intestinal illness which leads to diarrhea and vomiting. Much like other infectious diseases that cause these symptoms, norovirus can cause severe dehydration which has the potential to be fatal.

The Japan-based drugmaker’s intramuscular vaccine – known as TAK-214 – uses virus-like particles to mimic the antigen-coated surface of the norovirus. According to Takeda, an earlier clinical trial of the norovirus vaccine found that the drug was well tolerated among the 98 trial participants, but did not significantly reduce diarrhea or vomiting symptoms.

Norovirus is associated with approximately 20 percent of all cases of diarrheal disease worldwide, according to the Centers for Disease Control and Prevention (CDC). Their estimates suggest that the average person could expect to become ill from a norovirus infection between three and eight times in their lifetime.



As there is no approved drug to treat patients with norovirus, efforts have been focused on preventing transmission of the disease. Norovirus can be acquired from contact with infected individuals and contaminated food and surfaces.

Currently, there is no available vaccine to prevent norovirus infection. “We are excited to be on the frontline of development of a vaccine against norovirus,” said Rajeev Venkayya, president of Takeda Vaccines.

Around 3,400 participants will be enrolled in the Phase IIb clinical trial, according to Takeda. The company expects that the trial will run until August of 2017.


Keywords: Clinical Trials, Norovirus, Vaccine


| NEXT ARTICLE | MORE NEWS | BLOGS | VIDEOS | POLLS & QUIZZES | WEBINARS |

Share this with your colleagues!

MORE NEWS
Gilead’s Newest Hepatitis C Drug Gets FDA Approval

July 21, 2017 - Dominant player in the chronic hepatitis C virus (HCV) market Gilead has received US Food and Drug Administration (FDA) approval for its newest treatment, Vosevi.

Featured In: Pharmaceutical News


Detecting Alzheimer’s Biomarkers in the Blood Could Improve Early Diagnosis

July 20, 2017 - In an effort to improve rates of early diagnosis and intervention, researchers at Washington University in St. Louis have developed a blood test that can detect some of the hallmarks of Alzheimer’s disease.

Featured In: Biotech News


Insurance Coverage Under the Affordable Care Act Supports Clinical Trial Enrollment, Says Study

July 20, 2017 - Since the Patient Protection and Affordable Care Act (ACA) was passed in 2010, insurance approval for patients wishing to participate in oncology clinical trials has increased, according to a recent study published in the journal, Clinical Cancer Research.

Featured In: Clinical Trial News


LEAVE A COMMENT
 
  
THE XTALKS VITALS INDUSTRY BLOG

Manufacturing Control Strategies: What Pharmaceutical and Biotech Companies Need to Know

REGISTER FOR THESE WEBINARS

Outsourcing Pharmacovigilance: Pros and Cons and Lessons Learned


EDC and eSource: Combined for Better Data and Faster Insights


Using Model Reduction to Bridge the Quality Systems Pharmacology-Pharmacometrics Divide


How to Maximize Your Non-GLP Toxicology Studies: A Guide for Optimal Design and Methodology


Copyright © 2016-2017 Honeycomb Worldwide Inc.