Upcoming Webinars Archived Webinars Training Vitals Host A Webinar About Get Updates Contact

Clinical Trial Results Released For Herpes Vaccine

XTALKS VITALS NEWS

Herpes

All 17 of the participants in the small study reported that the three-shot vaccine was more effective at reducing herpes symptoms, compared to approved antiviral medications.

Tweetables from this article:

Tweet: Antiretroviral drugs are currently the only regulator-approved treatment for #herpes http://ctt.ec/Q3VbS+ Antiretroviral drugs are currently the only regulator-approved treatment for herpes.

Share this!

October 19, 2016 | by Sarah Hand, M.Sc.

Biotech company, Rational Vaccines has released promising data from their Phase I human clinical trial testing their Herpes vaccine candidate, Theravax. According to a press release issued by the company, the live-attenuated herpes vaccine could be a “functional cure” for those suffering from herpes simplex virus 1 and 2 (HSV-1 or HSV-2) infections.

The clinical trial sought to determine how safe and tolerable the Theravax vaccine was in patients with recurrent genital herpes. All 17 of the participants in the small study reported that the three-shot vaccine was more effective at reducing herpes symptoms, compared to approved antiviral medications.

Patients reported an average 3.2 reduction in the number of days they experienced herpes-related symptoms per month, compared to their previous experience taking antiviral drugs. Lead by head researcher, inventor and Chief Science Officer of Rational Vaccines, Dr. William Halford, the clinical trial was the first human trial of a live-attenuated therapeutic herpes vaccine.



“Doctors have been trying to manage genital herpes for 30 years with acyclovir-like antiviral drugs, and the approach has not stopped the spread of herpes,” said Halford, who has been working on Theravax in preclinical studies for over 10 years. “Over one million people per week continue to be newly infected with HSV-1 or HSV-2. It is time to offer herpes sufferers a 21st century solution with the potential to not only better treat herpes, but to simply stop the spread of the disease.”

One in six people in the US between the ages of 14 and 49 suffers from genital herpes. In addition to the painful symptoms of infection, HSV-1 can cause blindness and encephalitis.

Antiretroviral drugs are currently the only regulator-approved treatment for herpes. Rational Vaccines continues to follow patients who participated in the Phase I clinical trial, in an effort to monitor symptoms of HSV-2 infection.

“This is a very exciting time when it comes to medical innovations. Dr. Halford has created a safe and effective vaccine,” said Agustin Fernandez III, CEO of Rational Vaccines. “Dr. Halford's research and our company's recent clinical trial have opened the door to a better world where herpes no longer has to be suffered in silence, but can be treated and prevented.”


Keywords: Clinical Trial, Vaccine, Biotech


| NEXT ARTICLE | MORE NEWS | BLOGS | VIDEOS | POLLS & QUIZZES | WEBINARS |

Share this with your colleagues!

MORE NEWS
Lavazza Acquires Controlling Stake in Canada’s Kicking Horse Coffee

May 26, 2017 - Italian coffee company Lavazza, has secured an 80 percent equity stake in Canadian organic and fair-trade coffee company Kicking Horse Coffee, in a deal worth CAD$215 million.

Featured In: Food News


FDA First: Keytruda Approved for Cancer Treatment Based on Biomarker Alone

May 25, 2017 - For the first time, the FDA has approved a cancer treatment for solid tumors based on the presence of a biomarker, as opposed to specifying a tissue of origin.

Featured In: Biotech News


One Year of Medically Assisted Dying in Canada

May 25, 2017 - In June of 2016, the federal government of Canada passed legislation to legalize medically assisted dying.

Featured In: Life Science News


LEAVE A COMMENT
 
  
THE XTALKS VITALS INDUSTRY BLOG

Top 5 Most Impactful Tweets in Life Sciences During the Last Week

REGISTER FOR THESE WEBINARS

EU IVD Regulation: Top Five Changes for Medical Device Manufacturers to Consider


Thermal Processing Systems for the Food Industry: A Guide to Selecting Thermal Equipment and Technology


Rare Disease & Orphan Drug Development: Cost-Efficient Trial Design to Minimize Cash Burn


eTMF Workflows: Active eTMF to Improve the Quality of Clinical Trials


Copyright © 2016-2017 Honeycomb Worldwide Inc.