Upcoming Webinars Archived Webinars Training Vitals Host A Webinar About Get Updates Contact

Which Antioxidant is Right for Your Nutraceutical Product?

THE XTALKS BLOG

Astaxanthin

For nutraceuticals manufacturers, it’s important to choose a highly-potent antioxidant which is sustainable to produce and can easily be formulated into a number of product forms.

Share this!

May 3, 2017 | by Sarah Hand, M.Sc.

Despite their best efforts to eat a balanced diet, consumers are increasingly aware that they may not be getting all the micronutrients necessary to maintain good health. For decades, consumers have been turning to dietary supplements and nutraceuticals to support their healthy lifestyle.

The global dietary supplements market is growing; in 2016, the category was valued at $132.8 billion. In just five years, the market is expected to grow to $220.3 billion, according to a recent report from Zion Market Research.

“In many cases, we can’t keep up with the need for essential nutrients through our normal diet and that’s where antioxidant-containing nutraceuticals play an important role,” said Dr. Tryggvi Stefánsson, Science Manager at the Iceland-based ingredient supplier, Algalif.

Antioxidants in particular, represent a growing category of nutraceuticals. These compounds are able to mitigate some of the damage caused by free radicals – most often reactive oxygen species – on the lipids present in cell membranes. Once these membranes break down, they can trigger cell death and potentially health issues in a number of tissue types.

Fortunately, a number of naturally-occurring antioxidants are available to consumers to help prevent free radical damage. For nutraceuticals manufacturers, it’s important to choose a highly-potent antioxidant which is sustainable to produce and can easily be formulated into a number of product forms.

Vitamin C

Also known as ascorbic acid, vitamin C is an essential vitamin in the human diet. A number of forms of this popular supplement are available to consumers, including pills, capsules and powders, and it is commonly added to multivitamins.

Vitamin C is a non-enzymatic antioxidant capable of neutralizing potentially harmful reactive oxygen species. While many fruits and vegetables – such as broccoli, strawberries and oranges – are high in dietary vitamin C, most ascorbic acid is produced via a synthetic manufacturing process.



β-carotene

β-carotene is a provitamin which acts as a precursor to vitamin A in the body. This pigment gives vegetables like carrots their bright orange colour. Since β-carotene is converted to vitamin A in the body, it’s an important factor in maintaining eye health and vision.

Broccoli and onions are also good sources of dietary β-carotene, however individuals who take supplements need to be aware of a risk of overdose. Over consumption of β-carotene can result in toxic effects due to the body’s over production of vitamin A. Like vitamin C, β-carotene is a non-enzymatic antioxidant.

Astaxanthin

Compared to vitamin C and β-carotene, astaxanthin is a more powerful antioxidant capable of neutralizing cellular reactive oxygen species. In comparative studies, astaxanthin has been shown to be 6,000 times more powerful than vitamin C, and 5 times more powerful than β-carotene in capturing energy from a type of reactive oxygen species known as singlet oxygen.

Astaxanthin is lipid-soluble, and due to its molecular structure, it’s able to more efficiently sequester free radicals. According to Stefánsson, astaxanthin has been available in supplement form for the last 20 years, however interest in the powerful antioxidant has been increasing in the past decade.

Synthetic forms of astaxanthin are available, however natural sources have been shown to be most effective. Shrimp, lobster, salmon and other aquatic animals are high in astaxanthin, however a species of microalgae – Haematococcus pluvialis – synthesizes high levels of astaxanthin which makes it ideal for large-scale production of the antioxidant.

Best of all, astaxanthin can be formulated alongside other lipid-soluble nutrients – such as krill oil – to create multi-functional nutraceuticals. Astaxanthin’s mode-of-action and potency make it an attractive antioxidant to both nutraceutical manufacturers and consumers.

To learn more about formulating nutraceutical products with antioxidants – in particular, astaxanthin – register for Algalif’s webinar, “Not All Antioxidants Are Created Equal: Astaxanthin, The Antioxidant Powerhouse.



Keywords: Antioxidant, Nutraceutical, Dietary Supplement


| NEXT ARTICLE | MORE BLOG POSTS | NEWS | VIDEOS | POLLS & QUIZZES | WEBINARS |

 

        Share this with your colleagues!




        READ THESE NEXT
        The Top 4 Most Expensive Drugs in the US are Hepatitis C Treatments

        July 28, 2017 - In recognition of World Hepatitis Day, let’s take a look at the modern treatments capable of curing patients with hepatitis C.


        Manufacturing Top 5 Most Impactful Tweets from #AAIC17

        July 21, 2017 - This week, we’ll be rounding up 5 of the most impactful tweets from the Alzheimer’s Association International Conference (AAIC) held in London, England this year. The AAIC is the largest international conference dedicated to furthering Alzheimer’s disease and dementia research, uniting researchers from more than 70 countries across the globe. Here are the highlights from the research presented at the AAIC to keep you in the loop.


        Manufacturing Control Strategies: What Pharmaceutical and Biotech Companies Need to Know

        July 17, 2017 - Once implemented, a manufacturing control strategy is not only beneficial for pharmaceutical companies to help them avoid product launch delays and quality concerns; patients benefit greatly from being able to rely upon the quality and increased production efficiency of drug products.

        LEAVE A COMMENT
         
          
        THE XTALKS VITALS WEBINAR PRODUCTION TIPS BLOG

        6 Tips to Overcome Nervousness When Speaking in a Webinar

        REGISTER FOR THESE WEBINARS

        Data Integrity and the Manufacturing Control Strategy for Life Sciences Manufacturers


        Biosimilar Development: Lessons Learned from Early Clinical Studies


        Understanding Medical Device Regulatory Pathways in China and Japan


        Outsourcing Pharmacovigilance: Pros and Cons and Lessons Learned


        Copyright © 2016-2017 Honeycomb Worldwide Inc.