Upcoming Webinars Archived Webinars Training Vitals Host A Webinar About Get Updates Contact

Anticholinergic Medication Use May Increase Hospital Visits

XTALKS VITALS NEWS

Hospital

Both prescription and over-the-counter medications used to treat depression, pain and sleep problems, contain anticholinergic drugs.

Share this!

January 3, 2017 | by Sarah Hand, M.Sc.

A study conducted at Indiana University Center for Aging Research, Indiana University (IU) Center for Health Innovation and Implementation Science, and Regenstrief Institute, has found that older adults taking anticholinergic medications may visit the hospital more often. Both prescription and over-the-counter medications used to treat depression, pain and sleep problems, contain anticholinergic drugs.

According to the study – which was published in the journal, Phamacotherapy – as many as 50 percent of adults 65 years and older regularly use drugs with anticholinergic properties, with some individuals taking multiple anticholinergic medications on a regular basis. Using the Regenstrief Medical Record System, the investigators of the current study analyzed dispensing data for prescription drugs to determine how much of these drugs patients are taking, and compares them to hospital and emergency department visits.

“Anticholinergics, the medications that block acetylcholine, a nervous system neurotransmitter, have previously been implicated as a potential cause of cognitive impairment, by us and by other researchers,” said lead researcher, Dr. Noll Campbell, IU Center for Aging Research and Regenstrief Institute investigator. “This is the first study to calculate cumulative anticholinergic burden and determine that as burden increases, so does healthcare utilization in the U.S. -- both outpatient and inpatient.”



Campbell and his colleagues found that daily use of a drug with mild anticholinergic properties for one year, increased a patient’s chances of being admitted to the hospital by 11 percent. Anticholinergic drugs used to treat heart conditions, such as hypertension, are classified into the mild group.

Taking a strong anticholinergic drugs – such as a sleeping pill – on a daily basis, increased the likelihood of inpatient admission by 33 percent. These findings are just the latest in a decade’s worth of patient safety studies of anticholinergic medications, conducted at the IU Center for Aging Research.

“As baby boomers age and the number of older adults increases, it is especially important to recognize the negative impact of anticholinergic medications on the aging brain and healthcare delivery cost,” said Dr. Malaz Boustani, Chief Innovation and Implementation Officer of IU Center for Health Innovation and Implementation Science. “There is a powerful association between these harmful medications and potentially avoidable cognitive impairment and increased visits to the doctor, the ER and the hospital.”

Campbell advices patients currently taking anticholinergic drugs to talk to their healthcare providers about alternative medications. “This new study provides stronger motivation to design and conduct de-prescribing studies to determine safe ways to take individuals off anticholinergic medications in the interests of preserving brain health and decreasing healthcare utilization rates and their potential costs,” said Campbell.


Keywords: Hospital, Healthcare, Medication


| NEXT ARTICLE | MORE NEWS | BLOGS | VIDEOS | POLLS & QUIZZES | WEBINARS |

Share this with your colleagues!

MORE NEWS
Amgen Identifies Issue with Patient Access to PCSK9 Inhibitor

March 23, 2017 - Most US patients hoping to get their PCSK9 inhibitor medications covered by their prescription drug plan are being denied, according to two new studied conducted by Amgen.

Featured In: Biotech News


Smartphone App Created Using Apple’s ResearchKit Used to Conduct Asthma Clinical Studies

March 22, 2017 - Researchers at the Icahn School of Medicine at Mount Sinai have conducted a large-scale, observational study of asthma patients using the Apple ResearchKit framework and the Asthma Health app on patients’ iPhones.

Featured In: Clinical Trials News


IBS Patients Taking Viberzi May Be at Increased Risk of Pancreatitis

March 22, 2017 - According to a recent drug safety communication issued by the US Food and Drug Administration (FDA), patients with irritable bowel syndrome (IBS) with diarrhea should not be treated using Viberzi (eluxadoline), if they do not have a gallbladder.

Featured In: Drug Safety News

LEAVE A COMMENT
 
  
THE XTALKS VITALS LIFE SCIENCE BLOG

Will Pharmaceutical Serialization Solve All of Our Drug Counterfeiting Problems?

REGISTER FOR THESE WEBINARS

How to Improve the Speed and Efficiency of Your Clinical Trials


High Performance Computing for High Content Screening - A Case Study


The FDA Guidance on the Assessment of Abuse Potential of Drug – A Critical Review


Treatment of Psoriasis: Improvements Through Clinical Trials


Copyright © 2016-2017 Honeycomb Worldwide Inc.