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Advancing Bioabsorbable Scaffolds with Polymer Technology

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Date: September 14, 2017 (60 minutes)

Featured Speakers:

A great deal of recent clinical data suggests that bioabsorbable vascular scaffolds (BRS) are indeed expected to be the next revolution in endovascular therapy. In contrast to traditional metallic stents, the body has the ability to break down and absorb the polymers used to make these scaffolds. BRSs have been clinically shown to afford restored vasomotion, late luminal enlargement, and reduced angina; all benefits of a new vascular restoration therapy that is expected to improve the life of many patients.

While the day where BRS becomes the standard of care is fast approaching, transitioning from a permanent metallic platform to a transient polymeric platform has been a slow evolution and not without its challenges. Compared to most metals, polymers inherently possess a lower strength and toughness, thereby increasing the risk of scaffold recoil following deployment and strut fracture if traditional techniques of over expansion are used. These limitations have been largely overcome by an increase in strut thickness and by specialized polymer processing to induce molecular orientation. However, there remain concerns that the thicker struts could increase the risk of in-scaffold thrombosis and the risk of strut fracture will significantly limit the degree to which the scaffold can be over-expanded. Accordingly, further advancements in polymer chemistry and processing are needed and the ultimate success of cardiac and peripheral vascular restoration therapy via BRS will heavily depend on it.

Keywords: Medical Device, Cardiac Stent, Polymer Technology


Dr. Bruce Anneaux, Ph.D., Corporate Director, Research, Zeus

Dr. Anneaux earned his Masters and Ph.D. in Bioengineering from Clemson University. He has extensive experience in bioabsorbable polymer synthesis and processing with numerous innovations in related devices and components. Dr. Anneaux leads a diverse team of scientists and engineers within Zeus' ISO13485 accredited research facility and corporate analytical lab.

James M. Lindsey, III, Sr. Research Engineer, Zeus

Mr. Lindsey has Bachelor of Science degrees in Biological Sciences and Mechanical Engineering and a Masters in Bioengineering from Clemson University. For the past seven years, Mr. Lindsey has been the senior research engineer at Zeus. He specializes in bioabsorbable polymer design and synthesis, extrusion, and secondary processing.


Medical Device Engineers:

  • Design Engineer
  • Research Engineer
  • Manufacturing Engineer
  • Process Engineer
  • Materials Engineer
  • Quality Engineer


For more than 50 years, Zeus has delivered precision polymer solutions for the medical device industry. They specialize in precision extrusions of PTFE, FEP, PEEK, PFA, ETFE, PVDF, bioabsorbable polymers, and other engineered plastics. Headquartered in Orangeburg, SC, Zeus operates multiple facilities in North America and internationally, guaranteeing a stable supply of our products anywhere in the world. Their resources include a world-class team of polymer scientists and engineers that assist customers in elevating their concept from prototype to full-scale commercialization.

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